Review



flexx docking algorithm of the leadit environment  (BioSolveIT GmbH)

 
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    BioSolveIT GmbH flexx docking algorithm of the leadit environment
    Flexx Docking Algorithm Of The Leadit Environment, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexx+docking+algorithm/flexx+docking+algorithm/pmc08174488-308-11-20
    Average 90 stars, based on 1 article reviews
    flexx docking algorithm of the leadit environment - by Bioz Stars, 2026-09
    90/100 stars

    Images

    Related Articles

    Software:

    Article Title: Spiro-acridine inhibiting tyrosinase enzyme: Kinetic, protein-ligand interaction and molecular docking studies.
    Article Snippet: AC C EP TE D M AN U SC R Here, we evaluate spiro-acridines as inhibitors of tyrosinase, a key enzyme to melanogenesis.. For this purpose, the spiro-acridines 3-(acridin-9-yl)-N-benzylidene-2-cyanoacrylohydrazide (AMTAC-01) and 3-(acridin-9-yl)-2-cyano-N-(4-metoxybenzylidene)-acrylohydrazide (AMTAC-02) were synthesized and their enzymatic inhibition types and mechanisms were investigated.. In addition, the interaction of these compounds with the enzyme were studied by UV-vis spectroscopy, spectrofluorimetry, 1 H NMR titration as well as molecular docking.

    Article Title: Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study
    Article Snippet: .. For this purpose, FDA-approved NSAIDs were chosen to do docking simulations using the FlexX docking algorithm [ ] provided by LeadIT software package version 2.3.2 (BioSolveIT GmbH, Sankt Augustin, Germany). ..

    Binding Assay:

    Article Title: Spiro-acridine inhibiting tyrosinase enzyme: Kinetic, protein-ligand interaction and molecular docking studies.
    Article Snippet: AC C EP TE D M AN U SC R Here, we evaluate spiro-acridines as inhibitors of tyrosinase, a key enzyme to melanogenesis.. For this purpose, the spiro-acridines 3-(acridin-9-yl)-N-benzylidene-2-cyanoacrylohydrazide (AMTAC-01) and 3-(acridin-9-yl)-2-cyano-N-(4-metoxybenzylidene)-acrylohydrazide (AMTAC-02) were synthesized and their enzymatic inhibition types and mechanisms were investigated.. In addition, the interaction of these compounds with the enzyme were studied by UV-vis spectroscopy, spectrofluorimetry, 1 H NMR titration as well as molecular docking.

    other:

    Article Title: Biological evaluation and molecular modelling study of thiosemicarbazide derivatives as bacterial type IIA topoisomerases inhibitors.
    Article Snippet: FlexX and HYDE docking algorithms as implemented in LeadIT platform of BioSolveIT program were used with default parameters.



    Similar Products

    flexx docking algorithm of the leadit environment  (BioSolveIT GmbH)
    90
    BioSolveIT GmbH flexx docking algorithm of the leadit environment
    Flexx Docking Algorithm Of The Leadit Environment, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexx+docking+algorithm/flexx+docking+algorithm/pmc08174488-308-11-20
    Average 90 stars, based on 1 article reviews
    flexx docking algorithm of the leadit environment - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    flexx docking algorithm  (BioSolveIT GmbH)
    90
    BioSolveIT GmbH flexx docking algorithm
    DPP-4 interactions with piroxicam generated using the <t>FlexX</t> <t>docking</t> algorithm. ( a ) The binding pose view of piroxicam at the active site of DPP-4 and the hydrophobic surface visualized around the active site. ( b ) Binding mode of piroxicam interaction in the active site of DPP-4 (6b1E). The interacting residues are depicted with different colors: van der Waals (light green dotted line), pi–cation (orange), hydrogen bonding (dark green) and, finally, water hydrogen bond (light blue).
    Flexx Docking Algorithm, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexx+docking+algorithm/flexx+docking+algorithm/pmc06572294-72-13-25
    Average 90 stars, based on 1 article reviews
    flexx docking algorithm - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    docking algorithms flexx  (BioSolveIT GmbH)
    90
    BioSolveIT GmbH docking algorithms flexx
    DPP-4 interactions with piroxicam generated using the <t>FlexX</t> <t>docking</t> algorithm. ( a ) The binding pose view of piroxicam at the active site of DPP-4 and the hydrophobic surface visualized around the active site. ( b ) Binding mode of piroxicam interaction in the active site of DPP-4 (6b1E). The interacting residues are depicted with different colors: van der Waals (light green dotted line), pi–cation (orange), hydrogen bonding (dark green) and, finally, water hydrogen bond (light blue).
    Docking Algorithms Flexx, supplied by BioSolveIT GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexx+docking+algorithm/flexx+docking+algorithm/pmc03554869-95-29-32
    Average 90 stars, based on 1 article reviews
    docking algorithms flexx - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier
    flexx docking algorithm  (Astex Inc)
    90
    Astex Inc flexx docking algorithm
    DPP-4 interactions with piroxicam generated using the <t>FlexX</t> <t>docking</t> algorithm. ( a ) The binding pose view of piroxicam at the active site of DPP-4 and the hydrophobic surface visualized around the active site. ( b ) Binding mode of piroxicam interaction in the active site of DPP-4 (6b1E). The interacting residues are depicted with different colors: van der Waals (light green dotted line), pi–cation (orange), hydrogen bonding (dark green) and, finally, water hydrogen bond (light blue).
    Flexx Docking Algorithm, supplied by Astex Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/flexx+docking+algorithm/easydock/pm22203423-47-35-6
    Average 90 stars, based on 1 article reviews
    flexx docking algorithm - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    DPP-4 interactions with piroxicam generated using the FlexX docking algorithm. ( a ) The binding pose view of piroxicam at the active site of DPP-4 and the hydrophobic surface visualized around the active site. ( b ) Binding mode of piroxicam interaction in the active site of DPP-4 (6b1E). The interacting residues are depicted with different colors: van der Waals (light green dotted line), pi–cation (orange), hydrogen bonding (dark green) and, finally, water hydrogen bond (light blue).

    Journal: Pharmaceutics

    Article Title: Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study

    doi: 10.3390/pharmaceutics11050238

    Figure Lengend Snippet: DPP-4 interactions with piroxicam generated using the FlexX docking algorithm. ( a ) The binding pose view of piroxicam at the active site of DPP-4 and the hydrophobic surface visualized around the active site. ( b ) Binding mode of piroxicam interaction in the active site of DPP-4 (6b1E). The interacting residues are depicted with different colors: van der Waals (light green dotted line), pi–cation (orange), hydrogen bonding (dark green) and, finally, water hydrogen bond (light blue).

    Article Snippet: For this purpose, FDA-approved NSAIDs were chosen to do docking simulations using the FlexX docking algorithm [ ] provided by LeadIT software package version 2.3.2 (BioSolveIT GmbH, Sankt Augustin, Germany).

    Techniques: Generated, Binding Assay